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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3bb6a0e9c2a707947cb94c6d816a78002c21c55e8f817d13fabb285cc16d151' 
  AND token = '8E6rxKV7Il2UEEwc/ykMdAH+HsW6xf2B/02Gldkdy5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}