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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b300c7fd0b187ef604adc6501f3c7d3da8b80ce2ea23dd87686506c2dbb157' 
  AND token = '7D4wDTWPUjXoJoXUyVaNVxS5Mbi6wjfDWPG82FTeC5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}