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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c82f00f3c509ac2e353c1cce37617ebe5e2d6a70e18ad825eff55b3a2544a92' 
  AND token = 'fBCupFZ+2CFNrhBU0d56BOArAi3cZfDhwwSfKB9MXQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}