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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8245029cc3d8d29f6973513e80b1f459654c3ecc6ecb4368d6107a270e143b0a' 
  AND token = 'uGb5PrEoiyQd3O4ReoCBsSZAgpsRZkGTVCN5HJs1qAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}