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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4d123081be606c824051a2ad700699f60dbd2b1ccd958f9dedac49ec98e203' 
  AND token = 'arEuBNEcyXlHws0tz9B5XS/j2v6n2kfvy/1npLSGVpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}