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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550da74daec9f19f92ef419f6b178390b2e8b65c6b10a8cfb385aa522a37f335' 
  AND token = 'HbFOjvAJ4bWN4wsC443hIre8WUWRS/nxQ6ZBTlKV2a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}