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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f25932771aaab766b8bab71b3d3722e301c5003a91c2fde01010ca4588f173f' 
  AND token = 'aWC2e/HMgoV8sQgs1Z3kglMzIwPtYQ/VaMzop4c58MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}