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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f768b5b0ce75ee523c03fe01abbf8e3e771bd21684c03d3370ee7f8a9447f98d' 
  AND token = 'EPzSM+r050gR1RUbgWnq/LqtQJu6avyfnJaOQpzh9oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}