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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cc8579a601d5bfa139499fe3f67ee3b42ad2e267acfd5c07f1f4c677ff9471' 
  AND token = 'tl407ii4NIDMizTlmLOWRF+612hmd7a5E1qtYDRWclA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}