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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738631557c63c6a78b2343cfeddce947fd9011e9a2c923239f2344c6ef53bc3b' 
  AND token = '49TE7yahmCwuzYMTRuiGbsTdGOmHgt1UNbJc131JWpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}