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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1e9210ea465ea5068f5f93e75ba732bbc17306d3d69b9461b7cd979ebd2393' 
  AND token = 'hBW4vUBAfgU+IXSFFC/0MM0oIXE9+f9qhPnmQMbbOa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}