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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35b21c3a69d3ce8bdd56c27860cc3b7f10f17023337294ee61f558a70c844e4' 
  AND token = '6vdaCo0JeAd7ritnv/dVgL88IP4m60m9D9bXvh7ewIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}