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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581af9d5cc27a49fdaf58f5c2b7b56830554350862479cd768f9caaba2a25c4d' 
  AND token = 'GKxZM4oOdk9VZvyGlfDa7dr3i85dxUG/9ygvlwcZpqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}