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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b856455a8d1b64f5f77d97347652806f3ea435297ce8885cd9bee5d398802fb' 
  AND token = 'PdwJhQn2d9qSUVtTULNkNAeygr1imCR7soxqY98OehE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}