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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0827f7618af44fe5c887ced96398127b0a69d78a463985554df34e5e13b358' 
  AND token = 'hl1/KyzHcZbr0YzeKlQxxiZjz0BsKCm1889Jnb2a7fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}