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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c12c8e3d9afa45c6384d7b1713c42578e75c13013fb2a9dd6ce70c93f448b7' 
  AND token = 'vzB5zkt0fAO8LKYgAd/kp2+0lLG8qye5SdtBdxg8rjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}