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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec66e392d8ec4fe008ae6a3332e40c2cdacc0cc03ba6a1b895fe30e9549b918c' 
  AND token = 'YI8Pxb9H7bWyj1+q3egNFSlrTYrWsQzBnsqy73SpOIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}