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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a80b7b7834602218b440963acd9849a84b42b4e3d8725b15be86109390bbfd' 
  AND token = 'Wf5VTutbaZcvO7io6+TO/BokNOU1vXhJXW4vy3/MHec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}