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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489821695b505205e54d30acc147d5c3a78e32972a57c09c7c897e79ce6c16ce' 
  AND token = 'hisyiXqTCoRRDpBT22yPI7QkSF8c1sXMHuP2vIvO5VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}