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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39649f716563baab851a4c7c479a5ff29719aabde6e8b0a5ee1b9b072b40873' 
  AND token = '7ISPORRLkd7cE5DLL1LCt+JCQ0FJflu1yi0+EbpShZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}