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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22f542344edac1a30cbb2efd8fa38c65f1153336997e0283916844b2161a085' 
  AND token = '5OKQQNd1Vdu6TqBLySz4TCJIsa/2tIHAy5v/AJQ2XOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}