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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c968385f9e593002ac4b38a597edc957866be56d7fb211086600c3f02d84db' 
  AND token = 'DtNgwQA1JNwwmFAWU3ja6ZxcPQXS0TflfsfQlRo4XSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}