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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec1f689c9050971b3f7247f7e92c81fc80322eb631e46a776c7b5a21dab4e27' 
  AND token = 'G78R3lXluKf25cr2XErvMkiIcIYhF8zEDWOY55SE8LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}