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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab7d6ca8a518244665b465ce1536f56ab7fd8ec7cd9e77c4a24fa62c874844ca' 
  AND token = 'U0B3EWoUmGGqiuo3GgIDrJF/WvClmrrYPPyR6pTzlAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}