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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8f789c3ad7689406f520c58b1f8bc808d5fc1a2c412598e08dd45e43a4904d' 
  AND token = 'QEmbeIJwEGI+rys1lpT4aOgNMEcn5XkOr4Xll80RPO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}