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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c02b3c9edfcde56f1510f9a9ccdb2f59889624a3465a76791bd11fd7136c11b' 
  AND token = 'ua/BIVsdgg91A9Fz6yn1EC/9W3avAdZBMf3F36yPqrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}