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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47ddf01ff472a00a10e39de240586e08fdb1fd99ab6b0a366646bdcd0104c13c' 
  AND token = 'Yx+0qD9vem2yWWMeK4toOBq6AHuAzzWAw0LFUrW+nFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}