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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7777b390f300341e9c226b425eae6ec1278649e0a21ac6ad30f0d01bb0b8269' 
  AND token = 'RupTHgs4r2Twu1QnmMVKTYixmfblIb1yP8rAwbPtlwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}