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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164c1bfd01143b82d03e426e9883319c1be5db9247172b866f3ab7a83f4320ee' 
  AND token = 'IDigRZgMPA35bg+T7BwNQMFe6HF5aMpMtNCM+TbFUmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}