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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5eac3c959ac6d6343507c3331b26cc8e55d5be3e86811d7227d566b407f6a9' 
  AND token = 'lfUPhwZEqdFhdUB08+VGY58eVLlBC2jCTaOT2ZMsp9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}