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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ba9c2ec1982bc416e5f933e8d21d763f7c4bea57d12f727c0231cd37a9f93f' 
  AND token = 'D/tvwZ7xyrrve94Yyhj6uPhyWVHptFasPkijk717A7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}