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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0157d0f0021911e449c2b25b1abed5a406e832d87712903ee6cdc172d5921885' 
  AND token = 'TOLXuP5XBBmtf8t7rXdsAVRcpo5eS5nBmwLJ6hdR6p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}