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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b883d63ca2769e8d919568d9b6d1c030cf2b61a8d93350afcea408505b11df16' 
  AND token = 'qbOYY9WuP08uZwEdWdejrOLKewr+9xAdlG6t0cjMH0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}