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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c744b52547ab3e18268d935f9a27971f63a6141c595d23a93036338d169c7c' 
  AND token = 'PUIjNplLyu2oKKyO2WqeLNVJEa7oSxbSBnhScUkXW8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}