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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe603ad4802e4fd74bd5101cfc215fa926251aa6bcde4a80e5ad6b8d1ce11315' 
  AND token = 'Tbi5wRrH9Zr/+VF4WRBRyLMWApVpRdbXI8tUndh7LY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}