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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81cdb0e58767d0e3c2fef9024e10a27e2ccb6957928a0d94e131f77aa6c12a5' 
  AND token = 'TgkgIT1GWF4d38eLpqmikLQlUVtTEDyhKxSdNYO8xO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}