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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75202cedf08073667fe207121cb6617ae0e3aaa1954141a784432c4e95e2990a' 
  AND token = '+SGUlcqQY6AUc0NkDypH7kQMdpnT32LkX5RpBO0b5GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}