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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8d8b70200ade46e4541e831407703d502ee907fb1daff559c8a14e090f6efd' 
  AND token = 'YVmW9esIGOKodU/uSJpLsbm9l3sZrabpyDLWt5IfwXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}