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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c5f4448bc54ccd6727be233b42d3993ce9d67c555c4b93b502a6693066bc03' 
  AND token = '060YEzkqRdJTxOZA0TPo79F7H/NGBGVLQYbxEh/u7hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}