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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70a78cc81c3d19374286d478ee23f8d046ad18cd9e17c47ac7d9200d87f4912b' 
  AND token = 'R/wKbbrBH6xigMNrEFeDfVdJYFUMYdVCcJX3aKhIOGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}