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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5017a0f45e2b9ce2ee10064e98a023858665d8f7d37bbc8dfe5b0982c33b2e6' 
  AND token = 'f+nRSZZKENZIECm1hOmTWJ3LELORLdHfSTkLg+2zRgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}