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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee53c2ac7a109f5b2e7ee3983f0178b3a74b6039962d9a0d79e5b747a4119ec' 
  AND token = 'KVmVTDA+g96sPOIjVjeEiW57/BeCMkbiK6mftvLUL1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}