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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6382fea62eaf265ede1ec35179041e892758128ed4f8b1c21ae2d78dd49686a' 
  AND token = '/T4+DLG9SJ3gqbspFgiMat5IaZjrhk1143Q6RpfY01w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}