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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b1489dd1339cccc925e7415414162782d29779ee3254da5beeeeafc762a193' 
  AND token = 'aF3E+LA6b3BF2V0z3cTZpp0X1JrQYJ3RCN8jnHCUJzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}