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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809e4e0349496fa7e52e0373f7fb2ab40ad1acc13284edc49bb54b12262b0bc1' 
  AND token = 'f7vu9ezwLnRdaqgRk9rA7rNiBaG4XsNzMr7jJkjSXDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}