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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e82352e49d0a704f5b85cb4597e1ad1cf478319ed55234e0742ca2dbcebb88d3' 
  AND token = 'CdXS9Y+9XtWHaA0QkT4Ko/QbnkL2EFDi1DLYDvMuRrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}