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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454df2ca426966cdf9c7c4d9dcea84dc818a5f2a2d4502f2a61c7132b18889f5' 
  AND token = 'TC7P7L4j9nadhUpflP1NlRl7yq3HnmJ14LEybvNwKBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}