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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea9143a745592fb6113c56abb68ac308c8e46c8ccf63f3b91f2c924848a6b0a' 
  AND token = 'flSkNr3fJBkvSSGybPBMqHgWGIGBedWzcmhXWlfJ+20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}