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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521e49af37e197f4955d91ddf711608f0e51f11e8dbcb4e38c20799defacb325' 
  AND token = 'NgsNrU1jNDNA8g+7Z7536YzR99nUvYQGjcMcQdoS3LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}