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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd90e68774fd827cb2eb2fc0f338102b7b48339fee97021222a6cedbca16c5e' 
  AND token = 'H+ldGO8ckmh4ILtFp3DbmH94E7HLcdq4QWc0qcJkOJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}